The interleukin-10-1082 promoter polymorphism and cancer risk: a meta-analysis
نویسندگان
چکیده
منابع مشابه
A Meta-Analysis of Interleukin-10 -592 Promoter Polymorphism Associated with Gastric Cancer Risk
BACKGROUND Potential functional allele A/T single nucleotide polymorphism (SNP) of Interleukin 8 (IL-8) promoter -251 has been implicated in gastric cancer risk. METHODS We aimed to explore the role of A/T SNP of IL-8 -251 in the susceptibility to gastric cancer through a systematic review and meta-analysis. Each initially included article was scored for quality appraisal. Desirable data were...
متن کاملInterleukin-10 promoter polymorphisms and asthma risk: a meta-analysis.
Several studies assessed the associations of interleukin-10 (IL-10) polymorphisms with asthma in different populations. However, the results were inconclusive. The aim of the present study was to further assess the associations by the method of meta-analysis. Pubmed, EMBASE, Wanfang Database, China National Knowledge Infrastructure (CNKI) and Weipu Database were searched. Data were extracted in...
متن کاملThe -1082A>G polymorphism in promoter region of interleukin-10 and risk of digestive cancer: a meta-analysis
The -1082A>G polymorphism is located in promoter region of interleukin-10 (IL-10) and it could affect the production of IL-10. Numerous studies have investigated the association between IL-10 -1082A>G and risk of digestive cancer. However, the conclusion is still inconsistent. Here, we have performed a meta-analysis and systematic review to determine the association between the IL-10 -1082A>G a...
متن کاملassociation of interleukin-10 promoter polymorphism (-1082 g/a) and gastric cancer in andhra pradesh population of south india
background: gastric cancer (gc) is one of the most commonly diagnosed malignancies. genetic variation in genes encoding cytokines and their receptors, determine the intensity of the inflammatory response, which may contribute to individual differences in the outcome and severity of the disease. interleukin-10 (il-10) is a multifunctional cytokine with both immunosuppressive and antiangiogenic f...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2011
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/ger078